產品簡介

Fosfomycin (MK-0955) sodium 是一種能透過血腦屏障的廣譜抗生素，不可逆地抑制細胞壁合成的早期階段。Fosfomycin sodium 對多種細菌具有殺菌活性，這些細菌包括耐多藥 (MDR)，廣泛耐藥 (XDR) 和耐全藥 (PDR) 細菌。

體內實驗

1、請依序添加每種溶劑： PBS

Solubility: 100 mg/mL (549.39 mM); Clear solution; Need ultrasonic

＜1mg/ml表示微溶或不溶。

體外研究

Fosfomycin sodium is an epoxy antibacterial agent. Compared with other antibacterial agents, it acts by inhibiting the early process of cell wall synthesis.

Fosfomycin sodium has bactericidal activity against a variety of gram-negative and gram-positive pathogens, including broad-spectrum production β-Bacteria of lactamase and

carbapenemase, and against S. aureus strains with an inhibition rate of 90%.

Fosfomycin sodium displays extensive tissue penetration, can be used to research of infections of the CNS, soft tissues, bone, lungs, and abscesses.

體內研究

Fosfomycin sodium (80 mg/kg; i.v.-i.v. or i.v.-p.o.) displays the protective effect on the nephrotoxicity of double beckacin, and is not affected by different administration routes.

保存條件：2-8℃

注意事項：

1、為了您的安全和健康，請穿實驗服并戴一次性手套操作。